肝硬化并食管胃静脉曲张二级预防胃镜复查必要性及依从性的临床研究

Clinical study on the necessity and compliance of gastroscopy reexamination for secondary prevention in patients with cirrhosis complicated with esophageal and gastric varices

摘要:

摘要：目的??了解肝硬化并食管胃静脉曲张（EGV）二级预防胃镜复查的必要性及依从性。方法 选取2017年1月－2019年6月于该院首诊并内镜证实为食管胃静脉曲张破裂出血（EGVB）的患者77例为观察组，肝硬化并EGV序贯治疗的患者69例为对照组，比较两组术前血液生化检查指标、是否入住重症监护室、是否输血、内镜治疗情况、术后5?d（再）出血率、在院死亡率、住院天数、住院期间并发症/合并症，了解二级预防胃镜复查及序贯治疗的必要性，并分析胃镜复查依从性的影响因素。结果 观察组白细胞计数（WBC）、中性粒细胞计数百分比（Neu）、总胆红素（TBil）、血尿素氮（UREA）、凝血酶原时间（PT）、国际标准化比值（INR）、Child-Pugh分级（B级+C级）比例、终末期肝病模型（MELD）评分明显高于对照组（P?

Abstract:

Abstract: Objective?To learn about the necessity and compliance of gastroscopy reexamination for secondary prevention in patients with cirrhosis complicated with esophageal gastric varices (EGV).?Methods?From January 2017 to June 2019, 77 patients with EGVB confirmed by endoscopy were selected as the observation group, 69 patients with simultaneous segmental liver cirrhosis complicated with EGV sequential treatment were selected as control group. The indexes of preoperative blood test, whether they were admitted to intensive care unit, whether blood transfusion, endoscopic treatment, at 5 days postoperative bleeding rate, mortality in hospital, hospitalization days, complications/complications during hospitalization were compared between the two groups to understand the necessity of gastroscopic reexamination and sequential treatment during follow-up. Analysis of gastroscopy review compliance factors.?Result?The white blood cell count, percentage of neutrophils count, total bilirubin, blood urea nitrogen, PT, INR, Child-Pugh grade (grade B?+?C) and MELD score in the observation group were significantly higher than those in the control group (P?