内镜下逆行阑尾炎治疗术治疗急性非复杂性阑尾炎的疗效观察及对炎症因子的影响*

Endoscopic retrograde appendicitis therapy in treatment of acute non-complex appendicitis*

摘要:

摘要：目的??探讨内镜下逆行阑尾炎治疗术（ERAT）治疗急性非复杂性阑尾炎的临床疗效及对血清炎症因子水平的影响。方法 收集2017年1月－2018年9月广东省东莞市第八人民医院收治的急性非复杂性阑尾炎患者40例，随机分为研究组（n?=?20）和对照组（n?=?20）。研究组采用ERAT，对照组采用腹腔镜阑尾切除术（LA），比较两组患者的手术结果、并发症发生情况和手术前后血清白细胞介素-6（IL-6）、降钙素原（PCT）、肿瘤坏死因子-α（TNF-α）和C反应蛋白（CRP）等血清炎症因子水平的变化。结果 研究组术后下床活动时间、住院天数、手术时间和体温恢复正常时间明显少于对照组（P?

Abstract:

Abstract: Objective?To investigate the clinical efficacy of endoscopic retrograde appendicitis therapy (ERAT) in treatment of acute non-complex appendicitis and its effect on serum inflammatory factors.?Methods?40 patients with acute non-complex appendicitis from January 2017 to September 2018 were selected as the study subjects. They were divided into study group (n?=?20) and control group (n?=?20) according to the patients’ choice of treatment. ERAT was used in the study group, while laparoscopic appendectomy (LA) was used in the control group. The outcomes and complications of the two groups were compared. The changes in serum levels of inflammatory factors, such as interleukin 6 (IL-6), procalcitonin (PCT), alpha-tumor necrosis factor (TNF-α), and C-reactive protein (CRP) were compared between the two groups before and after operation.?Results?The time of getting off of bed activity, days of hospitalization, time of operation and time of temperature recovery in the study group were significantly shorter than those in the control group (P?