局麻下支气管镜钬激光治疗大气道狭窄的临床评价

Application and safety evaluation of holmium laser in the central airway obstruction

摘要:

摘要：目的??观察局麻支气管镜下钬激光治疗大气道狭窄的近期疗效及安全性。方法?收集山东大学附属省立医院2014年1月－2016年5月46例钬激光治疗的大气道狭窄患者共85例次，均经CT或气管镜检查证实，后予以钬激光治疗或联合冷冻或球囊扩张等处理，术中予以低流量吸氧并严密监测生命体征，术后定期复查并随访。结果?完全缓解5例次（5.9%），显著缓解69例次（81.2%），部分缓解11例次（12.9%），治疗失败0例次（0.0%），总体有效率100.0%；无死亡、大出血、气道内着火等严重并发症。结论?钬激光联合冷冻、球囊扩张治疗大气道狭窄安全性高，并发症少，近期疗效可靠。

Abstract:

Abstract: Objective?To evaluate the efficacy and safety of holmium laser in the therapy of central airway stenosis.?Methods?We collected 46 patients with central airway obstruction who was given 85 holmium laser treatments. All the airway stenosis were confirmed by CT or bronchoscopy. All the patients were treated with holmium laser treatment or combined with freezing or balloon dilation, and given low-flow oxygen and monitored for vital signs during the operation. Regular reexamination and follow-up were conducted after the operation.?Results?Total efficiency ratio is as high as 100.0%. Five cases (5.9%) completely relieved, 69 (81.2%) significantly relieved, 11 (12.9%) have partial response. No serious complications were reported.?Conclusion?Holmium laser is a safety method with satisfactory result in management of benign central airway stenosis.