Abstract:Abstract: Objective?To explore the clinical outcome of one-stage arthroscopically assisted ligament reconstruction in multi-ligament knee injuries, and comparing early versus delayed surgical treatment of multi-ligament knee injuries.?Methods?99 patients who underwent arthroscopic multi-ligament knee injuries reconstruction were evaluated retrospectively. According to time from initial trauma to surgery less than 21 days grouped as early surgical group (44 patients) and 21 days or longer defined as delayed surgical group (45 patients). The incidence of surgical complications was statistically analyzed, the VAS scores, knee joint Lysholm scores and IKDC scores before and after operation in each group were recorded and compared.?Results?All the surgical incisions healed by first intention, and there was no early complications. VAS scores, knee joint Lysholm scores and IKDC scores were improved significantly at the last follow-up (P?=?0.000). The VAS scores, knee joint Lysholm scores and IKDC scores before and after operation in each group were analyzed, the VAS scores of the last follow-up in the early surgical group were lower comparing with those in delayed surgical groups, and knee joint Lysholm scores and IKDC scores were higher improved at the last follow-up, however, significant differences were only noted on IKDC scores between the early or delayed surgical group (P?0.05).?Conclusion?For multi-ligament knee injuries, using one-stage arthroscopic surgery can achieve good stability of the knee and significantly improved knee function, and early surgical intervention would result in superior functional outcomes, when compared to delayed surgical intervention.