Abstract:Abstract: Objective?To study the effect of LeCampTM Nylon Rope ligation combined with Titanium clip in treatment of acute nonvariceal gastrointestinal hemorrhage (ANVUGIB).?Methods?From July 2015 to March 2019, 126 patients with acute nonvariceal upper gastrointestinal bleeding were treated with the above-mentioned methods. The time of hemostasis, the rate of re-bleeding after operation and complications, the rate of surgical operation after operation and the healing of ulcer were observed.?Results?All the 126 patients were successfully completed hemostasis treatment. The average operation time was 15 minutes (8 ~ 21 minutes). Endoscopic follow- up was completed in all patients in average of 6 months. All these ulcers healed well and no re-bleeding occurred.?Conclusion?The application of nylon rope combined with metal hemostatic clip in treatment of acute nonvariceal upper gastrointestinal bleeding is a safe and effective method.