Abstract:Abstract: Objective?To analyze the risk factors of occurrence of early rebleeding after endoscopic therapy of gastrointestinal bleeding.?Methods?167 patients with gastrointestinal bleeding who underwent endoscopic therapy from January 2016 to December 2018 were divided into rebleeding group (n = 33) and control group (n = 134) according to the presence or absence of early rebleeding after endoscopic therapy, and the medical records were reviewed to count related influencing factors, and multivariate Logistic regression analysis was used to analyze the risk factors of occurrence of early rebleeding after endoscopic therapy of gastrointestinal bleeding.?Results?Glasgow-Blatchford risk score (GBS), Rockall risk score (RS), acute upper gastrointestinal bleeding AMIS65 score, and hemoglobin value and platelet index at admission were independent influencing factors for occurrence of early rebleeding after endoscopic therapy of gastrointestinal bleeding (P < 0.05).?Conclusion?For patients underwent endoscopic therapy of gastrointestinal bleeding or patients with supra-thresholds of preoperative GBS, RS and AMIS65 scores and levels of hemoglobin and platelet index at admission, it is necessary to closely monitor and actively prevent early rebleeding.