Abstract:Abstract: Objective?To observe the feasibility and safety of disposable inflatable larynx mask in laparoscopic appendectomy under general anesthesia.?Methods?60 patients were selected for laparoscopic appendectomy from February to October 2017, with ASA Ⅰ to Ⅱ, age 16 to 65, and weight 42 to 75 kg. All the patients were randomly divided into two groups: tracheal intubation group (D group) and one-time inflatable larynx mask group (Z group). After induction of general anesthesia, D group patients were inserted into the tracheal duct, and Z group patients were placed into a disposable inflatable larynx mask. Before anesthesia induction (T1), when the tube (cover) is successfully inserted (T2), the tube (cover) is inserted after 5 min (T3), immediately before the tube (cover) is pulled out (T4) and immediately after pulling out (T5), these time nodes record changes in MAP and HR. The changes of airway peak pressure (Ppeak), end of exhalation carbon dioxide (PETCO2) and blood oxygen saturation (SpO2) were observed. The complications such as blood clotting, restlessness and cough were recorded during the recovery period of anesthesia, and the pain of throat and hoarseness were relieved after the follow-up of 48 h.?Results?The difference of MAP and HR in tracheal intubation group (D group) and disposable inflatable laryngeal mask group (Z group) was not statistically significant before anesthesia induction (P > 0.05), In group Z, the patients with disposable inflatable larynx mask (Z group) from T2 to T5 were significantly lower in MAP and HR than in patients with tracheal intubation (D group), and the difference was P < 0.05. The difference between Ppeak and PETCO2 in the two groups of patients was statistically significant compared to the pre-abdominal (P < 0.05). The comparative difference between Ppeak and PETCO2 showed P > 0.05, which was not statistically significant. Both the tracheal intubation group (D group) and the one-time inflatable laryngeal mask group (Z group) before and after the abdominal blood oxygen saturation SpO2 showed >0.05, without statistical significance, the difference between groups was also not statistically significant (P > 0.05). The incidence of cystic blood in group Z was similar to that of group D (P > 0.05); Patients in group D had significantly higher adverse reactions such as awakening restlessness, cough response, sore throat, and hoarseness during anesthesia recovery than group Z (P < 0.05); There was no significant difference between the two groups in the treatment of sore throat and hoarse voice (P > 0.05).?Conclusion?It is safe and effective to use a disposable inflatable larynx mask for laparoscopic appendectomy under general anesthesia. The disposable inflatable larynx mask can maintain respiratory tract patency and provide effective ventilation during surgery. It can significantly reduce intubation response. In maintaining hemodynamics stability and reducing respiratory complications, it is superior to tracheal intubation ventilation.