Abstract:Abstract: Objective?To investigate the effect of topical anesthesia of Tetracaine hydrochloride in oropharyngeal cavity on electronic laryngoscopy.?Methods?200 patients with electronic laryngoscopy were randomly divided into two groups by double-blind method, 100 patients in each group. One group was anesthetized with 1.0% Tetracaine in oropharyngeal cavity (control group), and the other group was sprayed with 0.9% normal saline (experimental group). Patients’ responses between the start of topical anesthesia and the end of the examination were evaluated according to self-designed evaluation criteria.?Results?Electronic laryngoscopy was successfully performed in both groups, and the difference in examination time was statistically significant (P < 0.05). The positive rate of pharyngeal discomfort in the control group were higher than those in the experimental group, the pharyngeal discomfort in the control group was more serious than that in the experimental group, it was statistically significant (P < 0.05).?Conclusion?Simple nasal surface anesthesia without oropharyngeal Tetracaine surface anesthesia will not affect the smooth completion of electronic laryngoscopy. Patients without oropharyngeal surface anesthesia had fewer pharyngeal adverse reactions, and the patients recovered into the diet quickly after the examination. The comfort level of the whole process of the examination was greatly improved. Without oropharyngeal anesthesia, the patient’s surface anesthesia and waiting time are shortened, and the examination efficiency is improved.