Abstract:Abstract: Objective?To compare the clinical efficacy and safety of 1470 nm dual wavelength laser and plasma in treatment of benign prostatic hyperplasia.?Methods?Clinical data of 364 patients with prostatic hyperplasia hospitalized from February 2015 to March 2018. 176 cases of benign prostatic hyperplasia were treated with 1470 nm dual wavelength laser and 188 patients were treated by plasma. The operative time, intraoperative bleeding, average time of hospital stay, postoperative urinary tract infection, postoperative urethral stricture and postoperative urinary incontinence were compared between the two groups.?Results?For the patients with smaller prostate volume (﹤ 50 g), there was no statistical difference between the two groups. For the larger prostate volume (≥ 50 g), the mean operation time of the laser group was significantly less than the average operation time of the plasma group. The difference was statistically significant, and the intraoperative bleeding and the average hospitalization days were significantly less than that of the plasma group. In the plasma group, there was no significant difference in postoperative urinary tract infection, urethral stricture and genuine urinary incontinence.?Conclusion?For small volume prostate can be considered 1470 nm dual wavelength laser and plasma treatment for large volume prostate, 1470 nm dual wavelength laser group has a great advantage.