荧光支气管镜对中央型原发性肺癌患者 诊断和治疗的指导价值

Clinical value of auto fluorescence bronchoscopy for central primary lung cancer

摘要:

目的 观察分析荧光支气管镜（AFB）诊断中央型原发性肺癌的临床价值。方法 选取该院接受单纯性白光支气管镜检查（WLB）和AFB、WLB联合检查的患者56例和113例，回顾分析其临床资料，分析比较两种不同检查方式诊断原发性肺癌的诊断价值。结果 WLB检查识别原发性肺癌的灵敏度为58.82%，联合检查识别原发性肺癌灵敏度为85.39%；WLB检查诊断中央型原发性肺癌的灵敏度、特异度、阳性预测值和阴性预测值分别为58.82%、40.90%、60.61%和39.13%；联合检查诊断中央型原发性肺癌的灵敏度、特异度、阳性预测值和阴性预测值分别为85.39%、62.50%、89.41%和53.57%；联合检查诊断中央型原发性肺癌的灵敏度在肺癌类型、肿瘤分期、有无淋巴结转移和病变位置等明显高于WLB组（P <0.05）。结论 AFB在诊断中央型原发性肺癌方面具有较高的价值，可用于指导其诊断和治疗。

Abstract:

【Objective】 To investigate the diagnosis and treatment of value of auto fluorescence bronchoscopy for central primary lung cancer. 【Methods】 56 patients received simple white light bronchoscope (WLB) and 113 patients received AFB were selected into this study and the diagnostic value of the two different ways was analyzed. 【Results】 The sensitivity of WLB for identification of primary lung cancer 58.82%, the sensitivity of joint inspection was 85.39%; sensitivity, specificity, positive predictive value, negative predictive value of WLB diagnosing with primary lung cancer was 58.82%, 40.90%, 60.61%, 39.13%; the sensitivity, specificity, positive predictive value, negative predictive value of joint diagnosis of primary lung cancer was 85.39%, 62.50%, 89.41%, 53.57%; the sensitivity of joint inspection diagnosis of primary lung cancer in lung cancer type, tumor stage, lymph node metastasis, the lesion location were significantly higher than those of WLB group (P < 0.05). 【Conclusion】 Auto fluorescence bronchoscopy (AFB) has a higher value in the diagnosis of central primary lung cancer and can be used to guide the diagnosis and treatment of this disease.