Abstract:【Objective】 To investigate the clinical epidemiological characteristics of hiatal hernia (HH). 【Methods】 Clinical, endoscopic, and histologic data were reviewed for patients with a HH diagnosis between 2009 and 2014 in a large hospital of Dongguan area, Guangdong. The prevalence, gender, age distribution, symptoms, classification, diameter of hernia, and concomitant disease of upper digestive tract were evaluated. 【Results】 A total of 71413 patients underwent endoscopy during the past six years. 121 patients (0.17%) were diagnosed with HH, of 0.23% patients were males and 0.10% patients were women (the ratio of man and women: 2.3 : 1). The prevalence of HH was 41.32% in the elderly, 19.83% in middle-aged and 38.84% in youth, respectively. 92.56% (112/121) patients were classified as type I, and 83.47% (101/121) patients were categorized by size as moderate (2~5 cm). There were 38.02% (46/121) patients in combination with reflux esophagitis, 3.31% (4/121) combined with Barrett's esophagus, and 28.93% (35/121) associated with gastroduodenal diseases. The main symptom of HH was epigastric discomfort, abdominal pain or distension, acid reflux, and heartburn. 【Conclusions】 HH should be paid more attention, because it's a common disease with a high proportion of reflux esophagitisis.