To explore the clinical effect of double-row suture-bridge technology on senile patients with osteoporosis in treating the avulsed fracture of humeral great tuberosity. Methods 18 senile patients with the avulsed fracture of humeral great tuberosity who had osteoporosis were treated with double-row suture-bridge technology from January 2016 to January 2018. They were followed from 6 months to 1 year and evaluated retrospectively the ROM of lift on forward, lift on abduction and outward rotation on abduction as well pre-operation and post-operation respectively. Meanwhile, the VAS score and ASES score were also evaluated respectively. Independent sample t test was used to evaluate the data. Results All these cases were healing without loosening of internal fixation and VAS score decreased from (6.83 ± 1.34) before surgery to (1.39 ± 0.70) after surgery as well as ASES score increased from (42.26 ± 10.32) before surgery to (88.95 ± 3.78) after surgery. The ROM above were all improved after surgery. It is statistically significantly. Conclusion It has excellent effect of the double-row suture-bridge technology on senile patients with osteoporosis in treating the avulsed fracture of humeral great tuberosity if you prepare it sufficiently.