SpyGlass DS胆道镜联合射频消融在肝外胆管癌诊治中的应用*

Application of SpyGlass DS choledochoscopy combined with radiofrequency ablation in diagnosis and treatment of extrahepatic cholangiocarcinoma*

摘要:

探讨SpyGlass DS胆道镜联合射频消融在肝外胆管癌诊断和治疗中的作用。方法 对临床疑诊为胆管癌的患者进行SpyGlass DS胆道镜检查，直视下观察胆管病变及活检，病理学检查证实胆管癌，不能手术切除的患者，接受胆管腔内射频消融（RFA）治疗。结果 15例患者成功进行SpyGlass DS胆道镜下活检病理学检查，3例外科手术治疗，12例完成胆管腔内RFA治疗，平均操作时间（36.8±4.2）min，无相关并发症。结论 SpyGlass DS胆道镜可以取得胆管癌标本，并明确病理学诊断，可进行胆管腔内RFA治疗，临床安全可行，疗效肯定，值得进一步推广。

Abstract:

To investigate the effects of SpyGlass DS choledochoscopy combined with radiofrequency ablation in the diagnosis and treatment of extrahepatic cholangiocarcinoma.?Methods?SpyGlass DS choledochoscopy was performed in patients clinically suspected with cholangiocarcinoma, bile duct disease was observed under direct vision, and biopsy was performed. Patients with unresectable cholangiocarcinoma confirmed by pathological examination were subsequently treated with intraductal radiofrequency ablation (RFA).?Results?15 patients successfully underwent pathological biopsy under the SpyGlass DS choledochoscope, 3 patients underwent surgical treatment, and twelve patients completed intraductal RFA. The mean operation time was (36.8 ± 4.2) min, and no related complications occurred.?Conclusion?SpyGlass DS choledochoscopy can obtain the specimen of cholangiocarcinoma for pathological diagnosis and enables intraductal RFA. It is clinically safe and feasible and has definite efficacy, so it is worthy of further application.