气管和支气管乳头状瘤临床分析

Clinical analysis of tracheal and bronchial papillomatosis

摘要:

总结气管和支气管乳头状瘤的临床特点及支气管镜下介入治疗情况。方法 回顾性分析2012年1月－2018年6月在应急总医院确诊的气管和支气管乳头状瘤的24例患者临床资料，进行分析、总结。16例患者有吸烟史，其中男患者13例；19例良性，5例恶变；9例病变为单发，占37.5%，累及2个及2个以上部位的共15例，占62.5%。喉部受累4例，中央型气道受累21例，二级支气管受累3例。肿瘤可以侵犯多个部位。结果 经支气管镜下介入治疗后，气道狭窄程度、气促分级、卡氏评分（KPS）均得到明显改善（P <0.01）。结论 气管和支气管乳头状瘤是气道内少见的肿瘤，多为良性病变，可以发生恶变，支气管镜下介入治疗是有效的治疗手段。

Abstract:

?To summarize the clinical characteristics and interventional treatment of tracheobronchial papillomatosis.?Methods?Clinical data of 24 patients with tracheobronchial papillomatosis from January 2012 to June 2018 were retrospectively analyzed. 16 patients had a history of smoking and 13 of them were men. 19 cases were benign and 5 were malignant change. 9 cases were solitary, accounting for 37.5%, involving 2 and more than 2 parts, accounting for 62.5%. Laryngeal involvement was found in 4 cases. Central airway were involved in 21 cases, and secondary bronchial involvement in 3 cases. Tumors can encroach on multiple sites.?Results?After tracheal interventional therapy, airway stenosis degree, dyspnea grade and KPS score were significantly improved (P < 0.01).?Conclusion?Tracheal and bronchial papillomatosis is a rare tumor in the airway, most of which are benign, while may have malignant change. Therapeutic bronchoscopy intervention is an effective treatment.