Abstract:Uniportal video-assisted thoracoscopic surgery (VATS) generally places the drainage tube in the center or side of the incision, which has a certain effect on the healing of the incision. Therefore, in the uniportal-VATS sublobar resection, we tried to replace the conventional thoracic drainage tube with a thinner central venous catheter, to see if this drainage method can achieve the effect of traditional drainage and reduce trauma and speed up the recovery of patients.?Methods?From September 2016 to March 2017, 60 uniportal-VATS sublobar patients have used thick tube and thin tube drainage randomly. Postoperative drainage, extubation time, incision healing, VAS scores, and BCS scores were compared.?Results?No matter whether the patient used thick tube drainage or thin tube drainage, there was no difference in postoperative drainage and extubation time. Incision healing in patients with thin-tube drainage is superior to that of patients with thick-tube, pain is reduced, and comfortable feeling is increased.?Conclusion?For patients with uniportal-VATS sublobar resection, in-situ thin tube drainage is safe and effective. Thin tube drainage is superior to thick tube drainage by comprehensive evaluation.