Abstract:To discuss the method and clinical application value of endoscopic radial incision in treatment of benign stenosis of colorectal anastomosis. Methods 46 patients with anastomotic stenosis underwent colorectal surgery from January 2015 to December 2016 were enrolled in the study, all the patients were adopted endoscopic radial incision to remove intestinal stricture, and all the operations were completed by the same doctor, treatment effect, intra-operative and postoperative complications were summarized, and followed up for 1 year, the symptoms of obstruction and anastomotic stenosis recurrence were assessed. Results 45 (97.8%) patients were successfully treated, the operation time was 18 (12 ~ 36) min, and the hospitalization days were 3 (2 ~ 6) d. The symptoms of intestinal obstruction were significantly improved in all the 45 patients (100.0%) who completed the treatment. There were no complications (0.0%) during or post-operation, such as bleeding, perforation or abdominal pain. 41 (91.1%) patients completed followed-up, and no symptoms of obstruction or anastomotic stenosis recurrence occurred during the follow-up period. Conclusion It is safe and effective for endoscopic radial incision in treatment of benign stenosis of colorectal anastomosis, and it is worthy to promote clinically.