Abstract:To compare the clinical efficacy of two-channel percutaneous nephrolithotomy (PCNL) for multiple kidney stones, which is a standard of visual precise puncture and conventional puncture. Methods 88 cases of renal multiple calculi treated with standard double-channel PCNL from July 2017 to August 2018 were analyzed. They were randomly divided into two groups: visual precision puncture standard double-channel group (n = 40) and conventional puncture standard double-channel group (n = 48). The time of establishing the first and second channels, operation time and the rate of hemoglobin decrease and postoperative blood transfusion rate, primary stone clearance rate and hospitalization timewere compared between the two groups. Results The establishment time of the first channel [(2.53 ± 1.52) vs (4.83 ± 1.82) min, t = 6.32, P = 0.000], the establishment time of the second channel [(3.02 ± 2.54) vs (6.92 ± 4.81) min, t = 7.42, P = 0.000], the operation time [(65.46 ± 15.54) vs (80.32 ± 13.62) min, t = 26.64, P = 0.000], and the decrease value of hemoglobin in the two group [(9.21 ± 2.52) vs (13.22 ± 3.53) g/L, t = 3.02, P = 0.000], postoperative blood transfusion rate [5.00% (2/40) vs 8.33% (4/48), χ2 = 0.01, P = 0.001], primary stone clearance rate [85.00% (34/40) vs 81.25% (39/48), χ2 = 3.21, P = 0.008], hospital stay [(5.52 ± 1.02) vs. (7.63 ± 1.21) d, t = 0.61, P = 0.001], the differences were statistically significant. Conclusion Compared with the conventional PCNL, the visualized precise puncture standard double-channel PCNL has the advantages of shortening the establishment time of the channel, shortening the operation time, reducing bleeding, high primary stone clearance rate and shortening the hospitalization time, which makes the clinical puncture operation safer and more accurate.