Abstract:To investigate the therapeutic effects of arthroscopic reconstruction in treatment of multi-ligaments injuries of knee joint. Methods From March 2008 to December 2017, 22 patients with multiple ligaments injuries of knee underwent arthroscopic reconstruction, including 15 males and 7 females with the average age of (40.1 ± 12.5) years old (ranging from 21 ~ 60 years old), whose anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) were reconstructed by autologous or allogenic tendons under arthroscopy and whose medial collateral ligament (MCL) or lateral collateral ligament (LCL) were repaired at the same time. 16 patients were treated with augmentation of MCL and 2 patients were treated with repair the LCL in addition to reconstruct ACL and PCL. 2 of them underwent early fracture fixation operations for combination of the lower limb fractures and received the arthroscopic operations after one and three months. The international knee documentation committee (IKDC), Lysholm knee score and Tegner activity scale were used for function evaluation. Ache situation was assessed by visual analogue scale (VAS). Results All the patients obtained successful arthroscopic reconstruction and repair. With an average follow-up of 25 months (5 ~ 48 months), there were significant difference between the last visit and pre-operation in Lysholm score [(85.10 ± 6.40) vs (21.60 ± 7.90), t = 34.80, P = 0.000]; IKDC score [(79.99 ± 5.12) vs (20.64 ± 8.35), t = 28.41, P = 0.000] and Tegner score [(3.77 ± 1.15) vs (0.45 ± 0.51), t = 12.36, P = 0.000] were significantly higher than that before surgery; The difference in the VAS scale [(0.45 ± 0.60) vs (6.73 ± 1.32), t = -20.37, P = 0.000] was statistically significant. Conclusion Arthroscopic reconstruction of ACL and PCL combined with repair or augmentation of the MCL and LCL simultaneously can obtain good stability and satisfying clinical results.