内镜黏膜切除术式活检对胃淋巴瘤的临床诊断价值探讨*

Clinical value of endoscopic mass mucosal resection biopsy for gastric lymphoma*

摘要:

摘要：目的 评价探讨内镜大块黏膜切除术式活检对胃淋巴瘤的临床诊断价值。方法 回顾性分析2012年1月－2018年6月在苏州大学附属第一医院确诊的原发性胃淋巴瘤（PGL）患者86例，对比经内镜下常规活检以及内镜大块黏膜切除术式活检的病理诊断准确率的差异。结果 经内镜下常规活检确诊为PGL患者31例，确诊率60.8%（31/51）；经内镜大块黏膜切除术式活检确诊34例，确诊率97.1%（34/35），明显高于内镜活检确诊率，差异具有统计学意义（P <0.05）；1例溃疡型PGL患者因消化道大出血行外科手术确诊。经内镜活检及内镜大块黏膜切除术式活检术后迟发性出血与穿孔发生率差异均无统计学意义（P >0.05）。结论 内镜大块黏膜切除术式活检对PGL诊断准确率高于内镜下常规活检方式，且操作简单、安全有效，可作为有效的临床诊断手段。

Abstract:

Abstract: Objective To evaluate the clinical value of endoscopic mass mucosal resection biopsy for gastric lymphoma. Methods A retrospective analysis was performed on 86 cases of primary gastric lymphoma from January 2012 to June 2018, and the difference in the accuracy rate of pathological diagnosis between endoscopic conventional biopsy and endoscopic mass mucosal resection biopsy was compared. Results 31 patients with primary gastric lymphoma were diagnosed by endoscopic conventional biopsy, the diagnosis rate was 60.8% (31/51); 34 cases were diagnosed by endoscopic mass mucosal resection biopsy, the diagnosis rate was 97.1% (34/35), significantly higher than the endoscopy biopsy diagnosis rate, the difference was statistically significant (P < 0.05); and one case of ulcerative primary gastric lymphoma was diagnosed by surgical operation due to massive gastrointestinal hemorrhage. There was no significant difference in the incidence of delayed bleeding and perforation between endoscopic biopsy and endoscopic mass mucosal resection biopsy (P > 0.05). Conclusion The accuracy rate of endoscopic mass mucosal resection biopsy for the diagnosis of gastric lymphoma is much higher than that of endoscopic conventional biopsy, and the operation is simple, safe and effective. It can be used as an effective diagnostic tool in clinical.