慢性腹泻患者结肠镜检查肠道准备方法的临床研究

Clinical study of bowel preparation methods for colonoscopy in patients with chronic diarrhea

摘要:

摘要：目的 探讨慢性腹泻患者在行结肠镜检查前的肠道准备方法。方法 回顾性分析2017年3月－2018年3月行结肠镜检查的慢性腹泻患者，共119例。其中，37例患者（A组）于结肠镜检查前4 h开始口服复方聚乙二醇电解质散（PGEP）139.12 g（2 000 ml）；42例患者（B组）于检查前4 h口服PGEP 208.68 g（3 000 ml）；另外40例患者（C组）检查前4 h服用PGEP 104.34 g（1 500 ml），检查前2 h口服50.00%硫酸镁（MgSO4）50 ml，再饮用温开水500 ml，至排泄液似清水样。应用Boston肠道准备量表（BBPS）评分，并对肠腔内气泡进行评分，比较3组患者肠道准备有效性、耐受性及安全性。结果 C组的进镜时间和退镜时间明显短于A组和B组；C组的BBPS评分明显高于A组和B组；C组的肠腔内气泡评分明显低于A组和B组；C组的肠道准备接受率、再次肠道准备接受率明显高于A组及B组；C组的总体不良反应评分明显低于A组及B组；差异均有统计学意义（P <0.05）。结论 慢性腹泻患者采用PGEP联合MgSO4进行结肠镜检查前肠道准备，其有效性、耐受性及安全性好。

Abstract:

Abstract: Objective To explore the method of bowel preparation for colonoscopy in patients with chronic diarrhea. Methods We retrospectively analyzed 119 patients with chronic diarrhea who underwent colonoscopy from March 2017 to March 2018. 37 patients (group A) received oral compound polyethylene glycol electrolyte powder (PGEP) 139.12 g (2 000 ml) at 4 hours before the examination; 42 patients (group B) oral PGEP 208.68g (3 000 ml) at 4 hours before examination; Another 40 patients (group C) taking PGEP 104.34 g (1 500 ml) at 4 hours before the examination, 50.00% magnesium sulfate (MgSO4) 50 ml orally at 2 hours before the examination, and then drinking warm water 500ml to the excretion fluid Like water samples. Boston Bowel Preparation Scale scores (BBPS) and bubbles in bowel lumen score were assessed. The effectiveness, tolerability and safety of intestinal preparation in three groups were compared. Results The colonoscopy time in group C was significantly shorter than that in group A and B; The total score of BBPS in group C was significantly higher than that in group A and group B; The bubbles in bowel lumen score in group C was significantly lower than that in group A and group B; The intestinal acceptance rate and re-intestinal acceptance rate in group C was significantly higher than group A and group B; The overall adverse reaction scores in group C was significantly lower than that in group A and group B; The difference was statistically significant (P ﹤ 0.05). Conclusion It is good effect of PGEP combined MgSO4 on bowel preparation before colonoscopy in patients with chronic diarrhea.