Abstract:Abstract: Objective To assess the safty, complications and efficacy of surgical treatment of chyluria with retroperitoneoscopic renal pedicle lymphatic disconnection (RRPLD) and open renal pedicle lymphatic disconnection (ORPLD) and provide a clinical reference. Methods 36 cases of chyluria were treated by renal pedicle lymphatic disconnection from January 2009 to October 2016. According to the surgical method divided into ORPLD group (14 cases) and RRPLD group (22 cases), respectively. The general information, operative time, intraoperative blood loss, postoperative intestinal recovery time, postoperative drainage duration, postoperative hospital stay, intraoperative complications were compared between the two groups. The patients were followed up 1 ~ 18 months, comparison of the long-term treatment of the two groups of patients. Results All the 36 patients were successfully treated with no intraoperative complications. There are no significant differences in the general information (age, male & female, left & right side) of patients between two groups (P > 0.05). The intraoperative blood loss in RRPLD group was significantly less than that in ORPLD group, the difference was statistically significant (P < 0.05). The incidence of incision pain in RRPLD group was lower than that in ORPLD group, the difference was statistically significant (P < 0.05). There was no significant difference between the operative time, postoperative intestinal recovery time, postoperative drainage duration and postoperative hospital stay (P > 0.05). There was no significant difference in recurrence rate between the two groups. Conclusions Retroperitoneoscopic surgery was less intraoperative blood loss, lower postoperative incidence of incision pain and more safe treatment of chyluria between retroperitoneoscopic renal pedicle lymphatic disconnection and open renal pedicle lymphatic disconnection, But the recurrence rate was not significantly reduced compared to open surgery; Retroperitoneoscopic renal pedicle lymphatic disconnection of the treatment of chyluria has definite curative effect, is the ideal treatment of chyluria surgery.