Abstract:Abstract: Objective To compare the effect and joint function of thoracic and lumbar spine fractures patients received paraspinal muscle approach and minimally invasive percutaneous approach surgery. Methods thoracic and lumbar spine fractures patients received internal fixation treatment from April 2014 to October 2015 were retrospectively analyzed and divided into paraspinal approach group and minimally invasive percutaneous approach group, separately received paraspinal muscle approach and minimally invasive percutaneous approach surgery. The operation condition, serum levels of traumatic molecules in the perioperative period and long-term functional recovery were observed. Results The operation time of paraspinal approach group was significantly shorter than the minimally invasive percutaneous approach group, intraoperative hemorrhage volume and postoperative drainage volume, postoperative bed time, hospitalization time have no significant difference with minimally invasive percutaneous approach group. serum CK, Myo and LDH contents of two groups patients after surgery had no significant difference; height ratio of anterior and posterior injured vertebra, Cobb angle and VAS score of two groups patients in 3 months, 6 months and 12 months after surgery had no significant difference. Conclusion Curative effect and trauma degree of paraspinal muscle approach and minimally invasive percutaneous approach surgery are equivalent and paraspinal muscle approach surgery’s procedure is more simple, operative time is shorter.