Abstract:Abstract: Objective To observe the effect of fiberoptic bronchoscope (FOB) combined with glidescope videolaryngoscope (GVL) for nasotracheal intubation in patients with obstructive sleep apnea syndrome (OSAS). Methods 90 patients with OSAS scheduled to undergo palatal pharyngoplasty were randomly assigned to three groups (n?=?30): direct laryngoscope group (M group), GVL group (G group) and FOB with GVL group (F group). SBP, DBP, MAP and HR were recorded before induction of anesthesia (T0), during tracheal intubation (T1) and at 1 min (T2), 5 min (T3) after tracheal intubation was completed. The intubation time was also observed. Cormack-Lehane (C-L) classification, the success rate of intubation, the incidence of pressing laryngeal external and using tracheal intuabting forceps, the incidence of nasal bleeding and hypoxemia were determined. Results The C-L classification was better in G and F group than M group (P?0.05). Compared with G and F group, the success rate of intubation was lower in M group (P?0.05). The incident of nasal bleeding, pressing laryngeal external and using tracheal intuabting forceps was lower in F group than M and G group (P?0.05). The incident of pressing laryngeal external was lower in G group than that in M group (P?0.05). Conclusion FOB combined with GVL for nasotracheal intubation can improve the success rate of intubation and reduce nasal bleeding in patients with OSAS.