膝关节骨性关节炎患者关节镜清理术后药物辅助治疗的临床应用效果

Clinical application of adjuvant therapy for arthroscopic debridement of osteoarthritis of knee joint

摘要:

观察探讨膝关节骨性关节炎患者应用关节镜清理术后药物辅助治疗的临床应用效果。方法 选取2015年1月-2016年6月于该院就诊的膝关节骨性关节炎114例，对患者按照入院先后顺序依次编号，将奇数号患者编入观察组（n =57），偶数号患者编入对照组（n =57），对照组患者仅给予关节镜清理术治疗，观察组患者在此基础之上给予玻璃酸钠及罗哌卡因药物注射治疗，观察各组患者的临床疗效。结果 观察组患者治疗后的临床优良率高于对照组患者（P <0.05）；观察组患者治疗后1、7、14、28和56 d的视觉模拟评分（VAS）均明显低于对照组（P <0.05）；观察组患者治疗后1、4、12、24和48周纽约特种外科医院（HSS）评分均明显高于对照组（P <0.05）。结论 在关节镜清理术治疗膝关节骨性关节炎的基础上增加玻璃酸钠及罗哌卡因药物注射，能够进一步提高患者的临床疗效，改善患者的临床症状和膝关节功能，且治疗的安全性高，具有临床推广使用价值。

Abstract:

To observe and discuss the clinical effect of adjuvant drug therapy after arthroscopic debridement in patients with knee osteoarthritis. Methods 114 cases of knee osteoarthritis were selected from January 2015 to June 2016. The patients were numbered in order of admission. The odd-numbered patients were enrolled in the observation group (n = 57) and the even-numbered patients were enrolled in the control group (n = 57). The patients in the control group were only treated with arthroscopic debridement, while the patients in the observation group were injected sodium hyaluronate and ropivacaine as an adjuvant therapy. Then observe the clinical efficacy of the two groups. Results The clinical excellent rate of the observation group was higher than that in the control group (P < 0.05); the visual analogue score (VAS) of the observation group was significantly lower than that of the control group (P < 0.05) on the 1st, 7th, 14th, 28th and 56th day after the treatment; and the HSS score of the observation group was obvious at the 1st, 4th, 12th, 24th and 48th week after the treatment. It was significantly higher than that in the control group (P < 0.05). Conclusion As an adjuvant therapy of arthroscopic debridement in treatment of knee osteoarthritis, the injection of sodium hyaluronate and ropivacaine can further improve the clinical efficacy, clinical symptoms and knee function of patients, and the safety of the treatment is high, so it is worthy of clinical application.