Abstract:To evaluate the clinical efficacy and safety of percutaneous endoscopic combined with percutaneous mesh-container-plasty in the treatment of spinal metastases with single segment of lumbar spine and nerve root compression. Methods Retrospective analysis of 19 patients with spinal metastases with lumbar vertebrae and nerve root compression with percutaneous endoscopic combined with percutaneous mesh-container-plasty from September 2012 to December 2016 was made. The operation time, intraoperative blood loss and hospitalization time were observed, and the curative effect was evaluated by visual analog scale (VAS) and MacNab criteria. According to MacNab standards to assess the excellent effect rate. Results The patient’s operation time (105.52 ± 14.25) min, intraoperative blood loss (35.58 ± 6.76) ml, hospitalization time (8.25 ± 2.14) d, the 3 d postoperative VAS score (3.18 ± 1.96) points, postoperative 3 months VAS score (1.67 ± 1.05) points, the postoperative VAS score was statistically significant compared with preoperative [(8.45 ± 1.35) points, (P < 0.05)]. According to the MacNab standard assessment of excellent efficacy rate of 84.21%. Conclusions Percutaneous endoscopic combined with percutaneous mesh-container-plasty has many advantages such as short operation time, less intraoperative blood loss, less trauma and quick recovery after surgery. It is a safe and effective minimally invasive surgery for the treatment of spinal metastases with single segment of the lumbar spine and nerve root compression.