Abstract:Abstract: Objective?To evaluate the safety of high frequency ventilation provided by anesthesia machine during interventional rigid bronchoscopy.?Methods?47 consecutive patients underwent rigid brochoscopy precedures were enrolled into the study. Anesthesia was induced with propofol 2.0 mg/kg and remifentanil 1.0?~?2.0?μg/kg, immediately followed by infusions of propofol, 8.0?~?10.0?mg/(kg·h), and remifentanil, 5.0?~?10.0?μg/(kg·h). When rigid bronchoscope was inserted into trachea, high frequency ventilation (tidal volume of 300?ml and frequency of 60 bpm) provided with anesthesia machine (Dr?ger, Germany) was initiated. Arterial blood gas analysis were performed at baseline, 15 min and 30 min after the surgery and at the end of the surgery. Episodes of hypoxemia were recorded. ?Results?47 cases were successively completed. Duration of surgery was (67.8?±?19.8) min. The lowest oxygen saturation were (95.3?±?8.4)%. Episods of oxygen saturation less than 90% occurred seven times. Two times occurred during brochoscopy insertion and other four times occurred during the operation. Arterial blood gas analysis showed mild hypercapnia.?Conclusions?High frequency ventilation provided by anesthesia machine can be safely used in the rigid bronchoscopy procedure.