复方聚乙二醇电解质散联合开塞露给药方法对结肠镜检查肠道准备的影响

Effect of polyethylene glycol electrolyte powder and enema on intestinal preparation for colonoscope examination

摘要:

摘要：目的??探讨复方聚乙二醇电解质散（PGEP）联合开塞露给药方法对结肠镜检查肠道准备的影响。方法?选择行结肠镜检查的患者600例，随机分为A、B、C 3组，各200例，A组于结肠镜检查前4?h口服2盒PGEP（139.12 g）清洁肠道，B、C组同法服药，B组检查前1?h开塞露40?ml 1次入肛；C组检查前1?h开塞露40?ml间隔30?min分2次入肛；3组患者检查前晚均进食流质、易消化饮食，检查当日禁食直至检查完毕。应用Boston肠道准备量表（BBPS）评分，并对肠腔内气泡进行评分，比较3组患者肠道准备的有效性、耐受性及安全性。结果?C组结肠镜检查时间（7.13±0.88）min，明显短于A组和B组（9.65±0.85）和（8.20± 0.76）min；C组BBPS总分（8.55±0.75）分，明显高于A组和B组（6.46±0.47）和（7.34±0.48）分；C组肠腔内气泡评分（0.23±0.10）分，明显低于A组和B组（0.85±0.34）和（0.55±0.42）分；C组再次肠道准备接受率（93.00%）明显高于A组和B组（78.00%，88.00%），差异均有统计学意义（P?<0.05）。3组患者肠道准备接受率和总体不良反应评分无明显差异（P?>0.05）。结论?口服PGEP联合结肠镜检查前1?h分次应用开塞露进行肠道准备，能显著提高肠道的清洁效果，且安全、简便。

Abstract:

Abstract: Objective?To discuss the effect of polyethylene glycol electrolyte powder (PGEP) and enema on intestinal preparation for colonoscope examination.?Methods?600 cases of constipation were randomly divided into three groups, 200 cases in each. Group A: oral administration of PGEP (139.12?g) at 4?h before colonoscope. Group B: oral administration of PGEP (139.12?g) at 4 h before colonoscope, and applied 40?ml enema at 1?h before colonoscope. Group C: the same method of oral administration of PGEP, and applied 20?ml enema at 1?h before colonoscope, and 20 ml enema at 30 min before colonoscope. Three groups of patients were eating liquid and easy to digest diet at the night before colonoscope, fasting until the check is completed. Boston Bowel Preparation Scale scores (BBPS) and bubbles in bowel lumen score were assessed. The effectiveness, tolerability and safety of intestinal preparation in the three groups were compared.?Results?The colonoscopy time in group C (7.13?±?0.88) min was significantly shorter than that in group A and B (9.65?±?0.85), (8.20?±?0.76) min; The total score of BBPS in group C (8.55?±?0.75) was significantly higher than that in group A and group B (6.46?±?0.47) and (7.34?±?0.48); The bubbles in bowel lumen score (0.23?±?0.10) in group C was significantly lower than that in group A and group B (0.85?±?0.34) and (0.55?±?0.42); the re-intestinal acceptance rate in group C (93.00%) was significantly higher than that in group A and group B (78.00%, 88.00%), the difference was statistically significant (P??0.05).?Conclusions?Oral PGEP combined the application of enema at colonoscope at 1 h before colonoscopy for intestinal preparation can significantly improve the intestinal cleansing effect which is safe and easy.