Abstract:Abstract: Objective?To compare the clinical efficacy of endoscopic versus microscopic approach to myringoplasty.?Methods?In this prospective study, the outcomes of 72 ears of 72 patients underwent myringoplasty were evaluated from January 2015 to December 2016 and randomly divided into group 1 and group 2. Group 1 underwent myringoplasty with an endoscopic technique (n?=?36), and Group 2 underwent myringoplasty with the conventional microscopic technique (n?=?36). The operating time, intraoperative blood loss, postoperative incision pain, average hospitalization time, hearing recovery and graft success rate were compared between the two groups.?Results?The operating time, intraoperative blood loss, postoperative incision pain, average hospitalization time of Group 1 were significantly lower than that in Group 2 (P?0.05). There were no significant differences between the preoperative and postoperative air-bone gap values (in dB) in either group (P?>?0.05). The difference between the graft success rate was not significant in either group (P?>?0.05).?Conclusions?Myringoplasty with an endoscopic technique holds many advantages: less pain, good efficacy, simple manipulation, reduced length of hospitalization and can get the same curative effect. Therefore, it is worthy of promoting clinical application.