Abstract:Abstract: Objective?To evaluate the clinical effect and safety of laryngeal mask combined with total intravenous anesthesia without muscle relaxant applied in fiberoptic bronchoscopy.?Methods?60 patients who scheduled for fiberoptic bronehoscopy were randomly divided into observation group (Group I, n?=?30) and control group (Group II, n?=?30). For the observation group, laryngeal mask combined intravenous anesthesia without muscle relaxant was used, while the control group received muscle relaxant. The blood pressure, heart rate and blood oxygen saturation in the two groups of different time points were recorded, and incidence of adverse reactions, patient satisfaction, anesthetic effectiveness and recovery time in the two groups were also compared.?Results?The HR and BP decreased and SpO2 elevated significantly at each observation time point after anesthesia compared with those before anesthesia in group I (P?0.05). There was no difference in BP in group II when removal of the laryngeal mask airway compared with those before anesthesia (P?>?0.05), but HR and SpO2 increased significantly (P?0.05). At the point of removal of the laryngeal mask airway, BP and HR were lower in group I than those in group II (P?0.05). There were no more adverse reactions in group I than that in group II (P?0.05).?Conclusion?It is a safe and effective alternative to painless fiberoptic bronchoscopy of laryngeal mask combined with total intravenous anesthesia without muscle relaxant and it is worthy of clinical promotion.