早期胃癌的临床病理特点与内镜下的表现分析

Clinicopathological features and endoscopic analysis of early gastric cancer

摘要:

摘要：目的  探讨早期胃癌的临床病理特点与内镜下的表现。方法 选择该院2008年1月-2016年12月早期胃癌患者120例作为研究对象。收集患者的临床病理资料及内镜检查资料。结果 早期胃癌患者年龄<55岁占30.8%，≥55岁占69.2%，男性占63.3%，女性占36.7%，主要症状为上腹部隐痛和食欲下降，分别占40.8%和22.5%，主要组织学类型为低分化腺癌和中分化管状腺癌，分别占48.3%和27.5%，分化型52例，占43.3%，未分化型68例，占56.7%，淋巴结转移14例，占11.7%，黏膜内癌66例，占55.0%，黏膜下癌54例，占45.0%。内镜下表现：早期胃癌胃窦部、胃体部、胃底部、贲门部的构成比分别为49.2%、26.7%、12.5%、11.7%，病灶直径<0.5 cm、0.5～1.0 cm、>1.0 cm的构成比分别为14.2%、38.3%、47.5%，大体类型Ⅰ型、Ⅱa型、Ⅱb型、Ⅱc型和Ⅲ型的构成比分别为10.8%、25.8%、11.7%、35.8%和15.8%。早期胃癌的分化程度和浸润深度与淋巴结转移有关（P <0.05），年龄、性别、病变部位、病灶直径、内镜下分型与淋巴结转移无关（P >0.05）。结论 早期胃癌男性多见，低分化腺癌比例高，内镜下见胃窦部好发，直径1.0 cm以上者较多，大体类型以Ⅱ型为主，未分化型癌和黏膜下癌淋巴结转移率高。

Abstract:

Abstract: Objective To investigate the clinicopathological features and endoscopic analysis of early gastric cancer. Methods 120 patients with gastric cancer from January 2008 to December 2016 were selected as subjects. The clinicopathological data and endoscopic data of these patients were collected. Results In Early gastric cancer patients, age < 55 years old accounted for 30.8%, ≥ 55 years old accounted for 69.2%, men accounted for 63.3%, women accounted for 36.7%. The main symptoms were upper abdominal pain and loss of appetite, accounted for 40.8% and 22.5% respectively. The main histological types were poorly differentiated adenocarcinoma and moderately differentiated tubular adenocarcinoma, accounting for 48.3% and 27.5%. The differentiation was 52 cases, accounting for 43.3%. The undifferentiated was 68 cases, accounting for 56.7%. The lymph node metastasis was 14 cases, accounting for 11.7%. The mucosal carcinoma was 66 cases, accounting for 55.0%, the submucosal carcinoma was 54 cases, accounting for 45.0%. Endoscopic found: The constituent ratios of antrum, stomach body, stomach bottom, cardia early gastric cancer gastric were 49.2%, 26.7%, 12.5% and 11.7%. The constituent ratios of diameter of lesion < 0.5 cm, 0.5 ~ 1.0 cm, > 1.0 cm were 14.2%, 38.3% and 47.5%. The constituent ratios of type I, IIa, IIb, IIc and iii were 10.8%, 25.8%, 11.7%, 35.8% and 15.8% respectively. The degree of differentiation and depth of invasion of early gastric cancer were associated with lymph node metastasis (P < 0.05). The age, sex, lesion location, lesion diameter, endoscopic classification were not associated with lymph node metastasis (P > 0.05). Conclusion The men early gastric cancer is more common,the proportion of poorly differentiated adenocarcinoma is high. The endoscopic sees the antral sinus is more, more than 1.0 cm in diameter is more, the general type is mainly type II. The lymph node metastasis rate of undifferentiated carcinoma and submucosal cancer are high.