直肠癌患者腹腔镜手术中淋巴结检出数量的相关因素研究*

Study on the related factors of lymph node detection number in rectal cancer patients underwent laparoscopic surgery*

摘要:

目的 探讨直肠癌腹腔镜手术淋巴结检出数量的相关因素。方法 选取2014 年1 月-2017 年1 月于该院行腹腔镜下微创手术治疗的98 例直肠癌患者为研究对象。统计患者一般资料[ 性别、年龄、体质 指数（BMI）]、术前影像学检查结果、临床病理资料（肿瘤大小、大体类型、TNM 分期、远处转移、组织 分化程度和浸润深度等）、手术情况（术者、手术时间）和术前放化疗情况。结果 年龄、BMI、肿瘤大小、 标本长度、浸润深度、术者情况、术前放化疗与直肠癌微创手术患者淋巴结检出数量有关（P <0.05），而性 别、TNM 分期、大体类型、组织分化程度、手术时间与直肠癌微创手术患者淋巴结检出数量无关（P >0.05）。 多元线性回归分析结果表明，BMI、肿瘤大小、标本长度、浸润深度、术者和术前放化疗是直肠癌微创手术 患者淋巴结检出数量的独立影响因素（P <0.05）。结论 患者因素、肿瘤状况、手术因素均及治疗情况与直肠 癌微创手术淋巴结检出数量有关。

Abstract:

Objective To investigate the related factors of lymph node detection number in rectal cancer patients underwent laparoscopic surgery. Methods 98 patients with rectal cancer who underwent laparoscopic surgery were selected from January 2014 to January 2010. All the patients general information [gender, age, body mass index (BMI)], preoperative imaging findings and pathological data (tumor size, gross type, TNM stage, distant metastasis, histological differentiation and depth of invasion, et al), surgery related data (experience of surgeon, operation time) and preoperative radiotherapy and chemotherapy were collected. Results The age, BMI, tumor size, length of specimen, invasive depth, surgeon and preoperative radiotherapy and chemotherapy was correlated with the number of lymph nodes in patients with laparoscopic surgery (P < 0.05), but gender, TNM staging, general type, histological differentiation, operation time were not associated with the number of lymph nodes detected in minimally invasive surgery for rectal cancer (P > 0.05). Multiple linear regression analysis showed that BMI, tumor size, length of specimen, invasive depth, surgeon and preoperative radiotherapy and chemotherapy were the independent influencing factors of lymph node detection in patients with minimally invasive rectal cancer (P < 0.05). Conclusion The factors of patients, tumor status, surgical factors and preoperative chemoradiotherapy are related to the number of lymph nodes in patients with rectal cancer.