内镜下治疗慢性胰腺炎的临床疗效及对患者腹痛症状改善程度的研究

Clinical effect on endoscopic treatment of chronic pancreatitis and the improvement of the symptoms of patients with abdominal pain

摘要:

目的 对内镜下治疗慢性胰腺炎（CP）的临床疗效进行观察，并分析患者腹痛症状的改善程度， 为临床提供参考依据。方法 选择该院2011 年7 月－ 2013 年6 月经内镜下治疗的CP 患者81 例，观察其疗 效、并发症和腹痛情况。结果 81 例患者手术均获成功，无死亡病例。术后1 周疼痛平均分为（2.29±0.14） 分，低于术前（7.13±0.27）分，差异有统计学意义（P <0.05）。术后1 周无痛、轻度疼痛和中度疼痛分别为 46.91%（38/81）、35.80%（29/81）和13.58%（11/81），均高于术前（P <0.05）。术后1 周重度疼痛为3.70%（3/81）， 低于术前56.79%（46/81）（P <0.05）。术后1 周脂肪泻和营养不良分别0.00%（0/81）和7.41%（6/81），均低 于术前25.93%（21/81）和37.04%（30/81），差异有统计学意义（P <0.05）。术后1 周血清淀粉酶平均浓度为 （74.18±2.75）u/L，低于术前（182.45±8.32）u/L，差异有统计学意义（P <0.05）。结论 内镜下治疗CP 并 发症较少，疗效可靠，具有微创、可重复等优点，可有效治疗慢性胰腺炎患者并能够有效缓解其腹痛。

Abstract:

Objective To explore the clinical effects on endoscopic treatment of chronic pancreatitis (CP) and the improvement of the symptoms of patients with abdominal pain, to provide basis for clinical treatment. Methods 81 patients with CP treated by endoscopic were selected from July 2011 to June 2013. Observe the efficacy, complications and bellyache. Results The operation of 81 patients were all successful, no death case. 1 week after the average pain was of (2.29 ± 0.14), lower than before the operation (7.13 ± 0.27), the difference was significant (p < 0.05). 1 week after, the operation, painless, mild pain and moderate pain were 46.91% (38/81), 35.80% (29/81) and 13.58% (11/81), were higher than those of preoperation (p < 0.05). The severe pain of after 1 week was 3.70% (3/81), lower than the preoperative 56.79% (46/81) (p < 0.05). 1 week after the operation, fatty diarrhea and malnutrition were 0.00% (0/81) and 7.41% (6/81), were lower than the preoperative 25.93% (21/81) and 37.04% (30/81), the difference was significant (p < 0.05). After 1 week, serum amylase concentration was (74.18 ± 2.75) u/L, was lower than the preoperative (182.45 ± 8.32) u/L, the difference was significant (p < 0.05). Conclusion Endoscopic treatment of chronic pancreatitis was fewer complications, reliable, and with the advantages of minimally invasive and repeated. It was effective in the treatment of patients with chronic pancreatitis and could effectively alleviate the pain.