儿童食管良性狭窄内镜下扩张疗效研究

Effect of endoscopic dilatation on children with benign esophageal stricture

摘要:

目的 探究食管良性狭窄儿童内镜下扩张疗效。方法 选取2013 年6 月-2016 年6 月该院及作 者本人在马里医院援外期间收治的共98 例食管良性狭窄儿童为研究对象，依据患儿狭窄病因将其分为A 组、 B 组和C 组，A 组11 例患儿为反流性食管狭窄，B 组43 例患儿为先天性食管闭锁术后狭窄，C 组44 例患儿 为化学性烧伤行食管狭窄。比较3 组患儿扩张治疗前狭窄段情况、扩张次数和并发症发生情况。结果 扩张 治疗前3 组患儿狭窄段平均直径差异无统计学意义（P >0.05），C 组患儿的平均长度大于A 组和B 组，且B 组大于A 组，差异具有统计学意义（P <0.05）。3 组患儿的扩张次数≥ 6 次的比例均高于<6 次，临床有效率 差异无统计学意义（P >0.05），C 组患儿的平均扩张次数高于A 组和B 组，且B 组高于A 组，差异具有统计 学意义（P <0.05）。C 组患儿的并发症发生率高于A 组和B 组，差异具有统计学意义（P <0.05）。A 组与B 组患者的并发症发生率无显著差异（P >0.05）。 结论 内镜下扩张对食管良性狭窄儿童有较好的临床疗效， 但化学性烧伤性食管狭窄患儿需要扩张较多次，且并发症较高，治疗难度较大。

Abstract:

Objective To study the curative effect of endoscopic dilatation in children with benign esophageal stricture. Methods 98 patients with benign esophageal stenosis from June 2013 to June 2016 were selected as the subjects of group A, group B and group C, 11 patients in group A were reflux esophageal stenosis, 43 children in group B were congenital esophageal atresia and in group C were 44 patients with chemical burn esophageal stricture. Then compare the three groups of children before the expansion of stenosis before the situation, the number of expansion and complications occurred. Results There was no significant difference in the average diameter of stenosis among the three groups (P > 0.05). The average length of the children in group C was higher than that in group A and group B, and group B was higher than group A, the difference was statistically significant (P > 0.05). The average number of expansion in group C was higher than that in group A and group B, and group B was higher than that in group A and group B higher than group A, the difference was statistically significant (P < 0.05). The incidence of complications in group C was higher than that in group A and B. The difference was statistically significant (P < 0.05). There was no significant difference in the incidence of complications between group A and group B (P > 0.05). Conclusion Endoscopic dilatation has a good clinical effect on children with benign esophageal stricture, but children with chemical burn esophageal stricture need to be expanded more often, while the complications are higher and the treatment is more difficult.