盐酸奥布卡因凝胶在结肠镜检查中的应用价值

Application of Oxybuprocaine Hydrochloride Gel in colonoscopy examination

摘要:

：目的 探讨盐酸奥布卡因凝胶在结肠镜检查中的应用价值。方法 结肠镜检查的患者1000 例， 随机分为实验组和对照组，各500 例，实验组镜检前采用盐酸奥布卡因凝胶10 ml（30 mg）进行肛周麻醉及润 滑，对照组采用石蜡油进行肛周及肠镜润滑，比较两组患者的一次插镜成功率、视觉模拟疼痛评分法（VAS） 评分、检查时间及术后并发症发生率。结果 实验组患者的一次插镜成功率（95%）高于对照组（76%），术 中疼痛评分低于对照组，检查时间缩短，差异有统计学意义（P <0.05）。结论 盐酸奥布卡因凝胶应用于结肠 镜检查能够有效地减轻了患者的疼痛不适，提高了一次插镜成功率，缩短检查时间，值得在临床上推广和使用。

Abstract:

Objective To explore the application of Oxybuprocaine Hydrochloride Gel in colonoscopy examination. Methods 1000 patients received colonoscopy examination were randomly divided into experimental group and control group, 500 cases in each. Oxybuprocaine Hydrochloride Gel was applied on anal region in the experimental group before endoscopy for perianal anesthesia and lubrication. Paraffin oil was used in the control group to lubricate perianal and enteroscopy. The success rate of primary insertion, visual analogue pain score (VAS) score, examination time and postoperative complications were compared between the two groups. Results In the experimental group, the success rate of primary insertion (95%) was higher than that of the control group (76%), and the pain score was lower than that of the control group.The examination time was shortened, and the difference was statistically significant (P < 0.05). Conclusions Oxybuprocaine Hydrochloride Gel applied to colonoscopy can effectively reduce the patient’s pain and discomfort, improve the success rate of primary insertion, shorten the examination time. And the method is worthy of clinical popularization and application.