胃底腺息肉的临床和内镜特征分析

Clinical and endoscopic characteristics of fundic gland polyps

摘要:

目的??分析胃底腺息肉（FGPs）的临床和内镜特征。方法 纳入2008年-2015年于首都医科大学附属北京世纪坛医院进行胃镜检查首次发现息肉并取活检/切除明确病理诊断的患者，进一步分析FGPs组和非FGPs组的临床和内镜特点。结果?共纳入867例胃息肉患者，其中FGPs者319例（36.8%）。FGPs组与非FGPs组相比较，前者息肉更小，平均（0.40±0.15）cm、单发息肉相对少（67.7%）、存在于胃底和胃体的比例更高（88.1%）和幽门螺杆菌（HP）感染率更低（6.1%），差异均具有统计学意义（P <0.05）。2008年-2015年，FGPs占胃息肉的比例和FGPs的检出率均逐年增加。结论?FGPs是胃息肉的常见类型，其检出率逐渐提高。与其他类型胃息肉相比较，FGPs好发于胃底和胃体，单发息肉相对少，且FGPs者HP感染少见。

Abstract:

Objective?To analyze the clinical and endoscopic characteristics of fundic gland polyps (FGPs).?Methods?A case-control study was carried out at the Affiliated Beijing Shijitan Hospital of Capital Medical University from 2008 to 2015. The patients who accepted an upper endoscopy and found the gastric polyps for the first time (diagnosed by pathology) were included in the study. Then, we analyzed the clinic and pathological characteristics of FGPs and non-FGPs.?Results?During the study period, 867 patients were enrolled, and 319 (36.8%) patients had FGPs. Compared the cases with the controls, the size of FGPs was smaller, an average is (0.40 ± 0.15) cm, single accounted for 67.7%, and 88.1% of FGPs were located at fundus and body. Helicobacter pylori infection of the cases detected was found in 6.1%, less than non-FGPs. There were statistically significant differences observed in these aspects. From 2008 to 2015, the proportion of FGPs in gastric polyps and the detection rate of FGPs are both gradually elevated.?Conclusions?FGPs are the common gastric polyps, and its detection rate is gradually elevated. Most of the FGPs are mainly located at fundus and body, and single. Helicobacter pylori infection detected in the patients who have FGPs is rare.