Abstract:Objective?To study the combination treatment of flexible/flexible sheath and rigid ureteroscopic lithotripsy (F-ul) for upper and middle ureteral stones.?Methods?The clinical data of patients diagnosed of upper and middle ureteral stones were collected. The treated group (110 cases): firstly treated with rigid ureteroscopic lithotripsy to broke and removed stones through flexible sheath, then the flexible ureteroscopic lithotripsy was used to broke and removed stones through flexible sheath; The control group (110 cases): traditional operation for ureter calculi. The clinical data was compared between the two groups.?Results?The effective ratio of treatment group is 90.0%, which was better than that of control group (87.3%) (P > 0.05). The operation time, stone processing time of treatment group were significantly shorter than those of control group (P < 0.05), and F-ul using time was significantly much more (P < 0.05). The hospitalization time and complication rate were no significantly difference between the two groups (P > 0.05).?Conclusion?The method of combining flexible/flexible sheath and rigid ureteroscopic lithotripsy for upper and middle ureteral stones was better than that of traditional operation, which worth to be popularize in clincal treatment.