不同频次肠道准备方法在肠镜检查中的多方面效果评估比较

Evaluation of various effects in different frequency of bowel preparation in the endoscopic examination

摘要:

目的??探索不同的肠道准备频次在结肠镜检查中的清洁度评分、结肠息肉检出率和被检查者的主观感受的差异。方法?收集2015年1月-2015年6月符合该研究的被检查者218例，随机分为3组；肠道准备的质量评估参照Boston肠道准备标准。等待检查期间行问卷调查了解被检查者的主观感觉，包括整体满意度和不适与进食情况、具体腹痛、腹胀等情况。结果?肠道清洁度3组差异均有统计学意义，其中A组和C组之间差异有统计学意义。3组之间的息肉检出率差异无统计学意义，肠道准备的整体满意度、主观感受等方面3组之间差异无统计学意义。结论?分次服用肠道准备用药在不影响被检查者主观体验的情况下可以提高肠道的清洁度，值得推荐。

Abstract:

Objective?To explore different approaches in administrating polyethylene glycol (PEG) solution in bowel preparation.?Methods?From January 2015 to June 2015, 218 patients eligible for this study were randomly divided into three groups (group A, 2 L PEG solutions 4 hours before colonoscopy; group B, 2 L PEG solutions 6 hours before colonoscopy; group C, 1 L PEG the night before and 1 L at least 4 hours before colonoscopy). The quality of bowel preparation was assessed on the basis of the Boston bowel preparation scale. A questionnaire was also completed to assess the subjective feelings of the preparation, including the overall satisfaction and discomfort with drug preparation, the feeling of abdominal distension, abdominal pain, nausea and vomiting, and the character of stool.?Results?In terms of intestinal cleanliness, statistical difference was shown between groups. Significant difference was found between group A and group C. However, the PDR between these three groups showed no statistical difference. No significant difference was found between the three groups considering the overall satisfaction and subjective feelings of preparation.?Conclusions?Without affecting the subjective feelings of patients, splitting dose of PEG solution improve the quality of bowel preparation and is worthy to be recommended.