经尿道1 470纳米半导体激光汽化术治疗前列腺增生的疗效分析*

Transurethral vaporization of the prostate using 1 470 nm diode laser in treatment of BPH*

摘要:

目的??探讨经尿道1 470 nm半导体激光治疗前列腺增生（BPH）疗效和安全性。方法?回顾性分析2015年12月－2016年4月该科应用1 470 nm半导体激光治疗BPH患者58例，观察其手术时间、手术前后血红蛋白、电解质和排尿情况等指标的变化。结果?该组手术全部成功，平均手术时间（48.2±16.3）min，术后24 h内测定血红蛋白（Hb）、电解质比术前轻度下降，但差异无统计学意义（P >0.05），随访1～3个月，国际前列腺症状评分（IPSS）、生活质量评分（QOL）、最大尿流率（Qmax）、残余尿量（PVR）较术前明显改善，差异有统计学意义（P <0.05），无电切综合征、勃起功能障碍和尿失禁等发生。结论?1 470 nm半导体激光经尿道前列腺汽化术具有学习曲线短、术中出血极少和疗效确切等优点，应用前景广阔。

Abstract:

Objective?To explore the efficacy and safety of Transurethral vaporization of the prostate using 1 470 nm diode laser in treatment of BPH.?Methods?58 cases BPH patients underwent transurethral vaporization of the prostate using 1 470 nm diode laser from Dec. 2015 to Apr. 2016 were retrospectively analyzed, including the mean operation time and compared hemoglobin, electrolyte, urinary symptoms, before and after surgery.?Result?Operations were successfully performed in all the 58 cases, with average operation time of (48.2 ± 16.3) min. No difference was found in either hemoglobin decrease or electrolyte decrease before and after surgery. The patients were followed up for 1~3 months, which revealed a significant reduction in IPSS and improvement in Qmax and PVR (P < 0.05), compared with pre-operation. No severe complications were reported, including transurethral resection (TUR) syndrome, urinary incontinence and impaired erectile function.?Conclusion?Transurethral vaporization of the prostate using 1 470 nm diode laser is a safe and effective therapy for BPH. It has advantages of short learning curve, very little blood loss, high efficacy. It has promising broad prospects.