Abstract:Objective?To compare the curative effect of anti-reflux plastic stent and common plastic stent in treatment of malignant biliary obstruction.?Method?22 cases of anti-reflux biliary plastic stent implantation and 30 cases of common bile duct stent implantation from March 2013 to April 2016 were selected as study subject, then compare the operation time, one-time success rate, postoperative pancreatitis, cholangitis, patency, differences in survival situation.?Result?There was no significant difference between the two groups in the aspects of the operation time, one-time success rate of recent cholangitis after surgery, postoperative pancreatitis (P > 0.05), but there was significant difference between the three aspects of long term patency, cholangitis, survival period (P < 0.05). ?Conclusion?The anti-reflux biliary stent has good long-term curative effect in treatment of malignant biliary obstruction, which worth of further exploration and research.