Abstract:Objective?To investigate the changes of vital signs of the patients in emergency endoscopic diagnosis and treatment; then assess and predict the patient’s tolerability of emergency endoscopy. Methods?87 patients with upper gastrointestinal hemorrhage were received emergency endoscopy and evaluated endoscopic tolerance, then explored correlation of endoscopic tolerance and patient age, complications, preoperative and intraoperative vital signs monitoring results. Results?The endoscopic preoperative heart rate, blood oxygen filling degree of patients had obvious difference (P <0.05), and 3 cases had consciousness change; endoscopic tolerance evaluation was 47 cases of tolerance and 32 cases of barely tolerate, 8 cases of intolerance, age between three groups had no significant difference (P >0.05), but the complication had significant difference (P <0.05). intolerance patients had preoperative rapid heart rates (118.4 ± 10.2) min, low blood pressure (94.5 ± 8.0) mmHg and blood oxygen filling degree (93.0 ± 2.1) %. The above index change in intraoperative is more apparent. Conclusion?Emergency endoscopy had significant negative effect on the vital signs in patients with moderately and severe upper gastrointestinal bleeding, but only a few patients can’t tolerate the endoscopic diagnosis and treatment, the reason include more complications, active bleeding, preoperative unstable vital signs, etc, therefore, endoscopic tolerance of the patients can be assessed and predicted through preoperative evaluation, and intraoperative careful observation.