经内镜乳头气囊扩张时间长短对胆总管结石治疗的有效性及安全性研究

Effectiveness and safety of different endoscopic papillary balloon dilation time in treatment of common bile duct stones

摘要:

目的 研究内镜下逆行胰胆管造影术（ERCP）术中乳头气囊扩张时间长短对胆总管结石取石的成功率及术后并发症的影响。方法 选取在该院行ERCP治疗的胆总管结石患者45例，随机分为短时气囊扩张组和长时气囊扩张组，分别比较两组患者的手术时间、术中及术后并发症发生率、住院天数和住院总花费等。结果 有48例患者成功入组，3例插管失败未能纳入研究，短时气囊组22例，长时气囊组23例，两组患者在结石大小、结石数目、胆总管直径、术后住院天数和手术总费用上差异无统计学意义（P >0.05），但在手术成功率、取石时间、术中并发症、术后胰腺炎发生率上长时气囊组明显优于短时气囊组（P <0.05）。结论 在行ERCP进行胆总管取石过程中，长时气囊扩张更有利于取石的成功率同时能减少术后相关的并发症。

Abstract:

Objective To study the effectiveness and safety of different endoscopic papillary balloon dilation time in treatment of common bile duct stones. Methods 45 patients with common bile duct stones received ERCP treatment, and they were randomly divided into short-term and long-term balloon dilatation group, then compared operative time, intraoperative and postoperative complication rate, hospitalization days and the total cost of hospitalization between the two groups. Results Short-term group included 22 people, the long term group included 23 people, there were no significant difference in stones' size, number and diameter of common bile duct between the two groups (P > 0.05), however, the success rate of surgery, time of stones' extraction, intraoperative complications and postoperative fistula were significant differences (P < 0.05). Conclusion Long-term balloon dilation during ERCP for treatment of common bile duct stones can improve the success rate of stone removal and reduce complications.