Abstract:Objective To compare and analyze the effect of laparoscopic surgery and open toperation of rectal cancer in middle or lower positions. Methods 128 patients with middle or lower rectal cancer were randomly divided into observation group and control group, 64 cases in each one, Laparoscopic surgery for observation group and control group using traditional open surgery. Operative time, blood loss, ambulation time, length of stay, postoperative complications, anus-preserving, the recurrence during follow-up were compared between the two groups. Results Blood loss, ambulation time, length of hospital stay, the observation group were significantly less than the control group (P < 0.05), operation time between the two groups have no obvious differences (P > 0.05). Nine patients in control group with complications, the rate was 14.1 %; postoperative complication were observed in 2 cases, the rate was 3.1 %; complication rate in observation group was significantly lower than the control group (P < 0.05). Anus-preserving rate was significantly higher in the observation group (P < 0.05); followed up for 8-47 months with an average follow-up (23.1 ± 6.4) months, relapse rates of the two groups have no significant difference (P > 0.05). Conclusions Compared with open operation,laparoscopic surgery is safe and effective, can reduce the surgical trauma and complications, shorten hospitalization time, improve the anus-preserving rate, worth clinical promotion.