气管镜介入联合局部丝裂霉素C治疗气管切开术后气道狭窄的临床研究*

Interventional bronchoscopy combined with local Mitomycin C in treatment of tracheotomy airway stenosis*

摘要:

目的  比较气管镜介入联合局部丝裂霉素C与气管镜介入治疗气管切开术后气道狭窄的疗效。 方法  将38例气管切开术后气道狭窄患者随机分为两组，观察组和对照组各19例。观察组采用气管镜介入联合局部丝裂霉素C，对照组采用气管镜介入治疗术。观察两组咳嗽、呼吸困难症状，治疗次数、住院时间和治疗费用。结果  观察组患者咳嗽症状积分、VAS评分较对照组低（P <0.05），两组患者呼吸困难程度差异无统计学意义（P >0.05）。观察组再治疗次数、住院时间和治疗费用低于对照组（P <0.05）。结论  气管镜介入联合局部丝裂霉素C治疗气管切开术后气道狭窄的疗效优于气管镜介入。

Abstract:

Objective To compare the effect of interventional bronchoscopy combined with local Mitomycin C and bronchoscope interventional therapy in treatment of tracheotomy airway stenosis. Methods 38 cases of patients after tracheotomy airway stenosis were randomly divided into two groups, observation group and control group with 19 cases in each group. The observation group with interventional bronchoscopy combined with local Mitomycin C, the control group using bronchoscopic interventional therapy. Two groups were observed cough, dyspnea symptoms, treatment times, hospitalization time and costs. Results The observation group of patients with cough symptom score, VAS score lower than the control group (P < 0.05), two groups of patients with no significant difference in the degree of dyspnea (P > 0.05). The observation group, the number of times of treatment, hospitalization time, costs less than the control group (P < 0.05). Conclusions Bronchoscopic interventional therapy combined with Mitomycin C local airway stenosis is more effective than interventional bronchoscopy after tracheotomy.