两种不同重量及大小的胶囊内镜之间胃肠通过时间及全小肠检查完成率的对比*

Comparison of gastrointestinal transit time and completion rates of two kinds of capsule endoscopy with different size and weight*

摘要:

目的  探究两种不同重量及大小的胶囊内镜之间胃通过时间（GTT）、小肠通过时间（SBTT）及全小肠检查完成率（CR）是否不同。方法  回顾性纳入因各种原因而接受了OMOM胶囊内镜检查或MiroCam胶囊内镜检查（比OMOM胶囊更小且更轻）的患者，对比分析了这两种不同重量及大小的胶囊内镜的GTT、SBTT以及CR。结果  共纳入1 448名符合条件的患者，其中OMOM组628例，MiroCam组820例。总体上，在工作时间校正后SBTT和CR方面，两组之间差异无统计学意义（P >0.05）。在克罗恩病或可疑克罗恩病患者中，OMOM组的GTT明显长于MiroCam组[（53.4±52.6）min比（41.1±47.9）min，P =0.022）]；在消化道出血患者中，OMOM组的GTT明显短于MiroCam组[（42.1±44.8）min比（62.0±78.6）min，P =0.016]。结论  总体来说，两种不同重量及大小的胶囊内镜之间的GTT、SBTT及CR没有明显差别，但在克罗恩病或可疑克罗恩病患者中，更轻且更小的胶囊内镜的GTT较短；而在消化道出血患者中，更轻且更小的胶囊内镜的GTT较慢。

Abstract:

Objective To investigate whether there has any difference of gastric and small bowel transit time and completion rates between two capsule endoscopes with different size and weight. Methods Clinical data of patients who had undergone OMOM or MiroCam (smaller and lighter than OMOM) capsule endoscopy were retrospectively studied. Comparison of gastric and small bowel transit time and completion rates were made between the two kinds of capsule endoscopy. Results 1, 448 patients (628 in OMOM group and 820 in MiroCam group) were finally included. In patients with Crohn's disease or suspected Crohn's disease, gastric transit time of OMOM was significantly longer than that of MiroCam [(53.4 ± 52.6) minutes vs (41.1 ± 47.9) minutes, P = 0.022]. In patients with gastrointestinal bleeding, gastric transit time in OMOM was significantly shorter than that in MiroCam [(42.1 ± 44.8) minutes vs (62.0 ± 78.6) minutes, P = 0.016). No significant difference in small bowel transit time or completion rate was found. Conclusions We conclude that the differences of gastric transit time, small bowel transit time and completion rates between the two kinds of capsule endoscopy with different size and weight are not significantly. Whereas, in patients with Crohn's disease or suspected Crohn's disease, gastric transit time of smaller and lighter capsule endoscopy is shorter in patients with gastrointestinal bleeding, but longer of gastric transit time in smaller and lighter capsule endoscopy.