【Objective】 To evaluate whether or not endoscopic mucosal resection and endoscopic submucosal dissection are efficient and safe for early gastric cancer. 【Methods】 The clinical data of patients whose pathological results were early gastric cancer between January 2008 and January 2013 were collected. Sixty-seven patients were included.The two groups from the en bloc resection rate, R0 resection rate, operation time, complication and recurrence rate were compared. 【Results】 En bloc resection and R0 resection rates of ESD group (93.5%, 77.4% respectively) were significantly higher than those of EMR group (50%, 41.6% respectively). Local recurrence rate in ESD group (3.2%, 1/31) was significantly lower than that of EMR group (19.4%). Mean operation time of ESD group (59.3±16.8) min was significantly longer than that of EMR group (31.7±17.8) min (P <0.05). Complications of perforation in ESD group was higher than that of EMR group, but there was not different between ESD group and EMR group on haemorrhage. 【Conclusion】 ESD, with higher cure rate and en bloc rate and a lower local recurrence rate, is superior to EMR for early gastric cancer.